Particle characterization in biological complex media (as serum, blood, urine and cell lysate) is foreclosed to traditional technologies because of the presence with relatively high concentration of a heterogeneous, polydisperse submicron component, as proteins, lipids, antibodies, vitamins which commonly share with particles the same size, especially if aggregates are present.
CLASSIZER™ ONE is the unique available instrument on the market able to distinguish between signals as coming from the test particles or other different components of the complex mixture. In this way, it is possible to easily perform analysis directly in the complex fluid where the particles are dispersed, without purification or filtration steps, which tipically are time-consuming techniques and alter the systems.
Real time monitoring opens new opportunities for understanding interactions between materials and biocomponents, in terms of sizing, concentration and structure.
On the contrary, SPES technology distinguishes between signals as coming from different components of a complex mixture. In this way, it is possible to easily perform analysis directly in the complex fluid where the particles are dispersed. A great improvement in the particle engineering process is possible: